| 1. | Mechanical injury to cartilage explants in culture also reduced autophagy proteins.
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| 2. | This data supports the development of therapies that will encourage autophagy.
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| 3. | Induced autophagy interfers with the action of the chemotherapy drug vincristine.
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| 4. | Knockdown of the PSMB7 gene may also induce autophagy in cardiomyocytes.
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| 5. | This inhibits autophagy, the major degradation pathway in eukaryotic cells.
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| 6. | Autophagy allows the orderly degradation and recycling of cellular components.
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| 7. | The first Keystone Symposia on autophagy was held in 2007 at Monterey.
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| 8. | In both cases, autophagy is observed to markedly increase.
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| 9. | Moreover, active mTOR supports tumor growth also indirectly by inhibiting autophagy.
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| 10. | Sorafenib treatment induces autophagy, which may suppress tumor growth.
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