Chronic respiratory acidosis also may be secondary to obesity hypoventilation syndrome ( i . e ., Pickwickian syndrome ), neuromuscular disorders such as amyotrophic lateral sclerosis, and severe restrictive ventilatory defects as observed in interstitial fibrosis and thoracic deformities.
32.
In chronic respiratory acidosis, what is the purpose of HCO3-( bicarbonate ), if it can't actually buffer the H + ( the elevated pCO2, resulting in the cause of the acidosis, would prevent buffering ? ).
33.
In cases of respiratory acidosis, the infused bicarbonate ion drives the carbonic acid / bicarbonate buffer of plasma to the left and, thus, raises the pH . It is for this reason that sodium bicarbonate is used in medically supervised cardiopulmonary resuscitation.
34.
This is commonly found in people with chronic respiratory acidosis from chronic lung disease such as Chronic Obstructive Pulmonary Disease ( COPD ), who can't breathe off their excess carbon dioxide owing to poor lung function, and retain bicarb in order to counteract the acidosis caused by the retained CO2.
35.
Side effects such as unconsciousness or coma, hyperemesis, nausea, seizures, convulsions, tachycardia, bradycardia, mydriasis, syncope, spontaneous urinating and defecating, shortness of breath, somnolence, respiratory acidosis, metabolic acidosis, collapse, lower limbs paralysis, chest pain, aggression and severe disturbance of behaviour were reported.
36.
Inhalation can be confirmed by one or more tests such as using a stethoscope to listen for abnormal lung sounds ( diffuse'wet'crackles and rhonchi ), performing blood gas tests to confirm a severe loss of lung function ( respiratory acidosis as a consequence of hypercapnia ), and using chest X-rays to look for patchy or streaked areas on the lungs.
